After Life imagines a post-mortem reunion of Pablo Picasso and Gertrude Stein. Stein believes her beloved Alice B. Toklas has conjured her back to life, while Picasso wonders which of his many lovers has called him up from the abyss. When both realize, to their disappointment, that their great loves are not present, the two towering figures discuss their lives, their complex relationship, and their activities during the Second World War. A young girl, a victim of the Holocaust, appears, and it is her questioning that has brought Stein and Picasso back from the dead.